Samples of blood are sent to laboratories to be examined and tested with chemicals in order to identify disease causing pathogens. Certain healthcare providers can have an in-house testing laboratory so that they can rapidly test blood samples, allowing for patients to receive quick results.
Accreditation bodies are independent organisations that provide assessments of the competence and performance of testing laboratories, based on internationally recognised standards. We are registered with the Care Quality Commission (CQC), ensuring that we provide the best care and service to all of our patients.
Blood testing laboratories situated in the UK are subject to regulations and laws, including:
The health and care professions council (HCPC) regulate the scientific and professional proficiency of all Biomedical scientists on their register. It is a legal requirement to be registered with the HCPC in order to practice in the profession.
To keep accreditation, laboratories should regularly perform internal quality management of their services, this usually involves a set of policies, procedures, and controls designed to ensure that testing is performed with the upmost quality, accuracy, and consistency, and that any issues are promptly managed, identified, and addressed. Quality management systems cover all aspects of the laboratory and its operations, from sample collections, to storage, and reporting of the results.
Further assessments can be carried out from external sources, typically by the regulator, these tests verify the accuracy and reliability of laboratories testing methods, blood testing labs in particular participate in EQA schemes. EQA is a process in which a third-party provider sends anonymized samples to be tested. The lab then carries out tests like normal, and reports the results back to the provider, who compares them to the expected values. This process helps to identify any potential biases, errors, or deviations for standard procedures and regulations, laboratories are expected to take corrective action immediately, if necessary.
Results of blood tests can vary slightly between different laboratories, one reason can be due to their analysis process having some form of variation, for example variations in testing equipment used although this must be regulated within each laboratory by performance of a validation study. This will ensure that variability is within the expected ranges for the particular biomarker of interest.
Furthermore, as with all blood tests, there can be changes within the body that can have an impact on blood test results, certain hormones and other biomarkers can fluctuate throughout the day. For example, testosterone levels in men are higher in the morning compared to night, this means that test results targeting testosterone can vary depending on the time of day the test is conducted.
Other factors to consider are variations such as, the time it takes to reach the laboratory, the temperature of the environment, and the how much blood is collected, although, these changes are often minor in nature and do not severely impact results. All results must be interpreted in line with clinical symptoms as good practice.
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